Shanghai Topwell Pharma Co., Ltd.
We are professional supplier of Monoclonal Antibody,Fusion Protein,Polypeptides &Bioactive Compounds,Therapeutic Antibodies,Active Pharmaceutical Ingredients.
Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
Description
Herceptin (trastuzumab) is a humanized IgG1 kappa monoclonal antibody that selectively binds with high affinity to the extracellular domain of the human epidermal growth factor receptor 2 protein, HER2. Trastuzumab is produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) culture containing the antibiotic gentamicin. Gentamicin is not detectable in the final product.
Trastuzumab is a sterile, clear, colorless liquid of pH approximately 6.0, which may contain a small amount of easily visible, white, amorphous trastuzumab particulates. trastuzumab is supplied at a concentration of 21 mg/mL, which contains 19.09 mg/mL α,α-trehalose dihydrate, 0.475 mg/mL L-histidine HCl monohydrate, 0.305 mg/mL L-histidine, and 0.085 mg/mL polysorbate 20, Water for Injection, and no preservatives.Name | trastuzumab |
CAS NO. | 180288-69-1 |
Type | Whole antibody |
Source | humanized (from mouse) |
Target | HER2/neu |
Clone | Monoclone |
Formula | C6470H10012N1726O2013S42 |
Molecular Weight | 146 kDa |
Antibody Form | Purified immunoglobulin |
Physical Form | Solution |
Grade Standard | Medicine Grade |
Place of Origin | China(Mainland) |
Storage | -70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light. |
