Ranibizumab

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Shanghai Topwell Pharma Co., Ltd.

Business Type:Manufacturer

Country/Region:China

Ddu Verified

HOT Rank

6/10

Product Information

  • Certification:ISO
  • Brand Name:Topwell
  • Place of Origin:China
  • Warranty:10 years

Description

    Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment designed for intraocular use. Ranibizumab binds to and inhibits the biologic activity of human vascular endothelial growth factor A (VEGF-A). Ranibizumab, which lacks an Fc region, has a molecular weight of approximately 48 kilodaltons and is produced by CHO expression system.
    Ranibizumab is supplied at a concentration of 20 mg/mL as a sterile, colorless to pale yellow solution, which contains 10 mM histidine HCl, 10% α,α-trehalose dihydrate, 0.01% polysorbate 20, pH 5.5.

    Name

    Ranibizumab

    CAS NO.

    347396-82-1

    Type

    Fab fragment

    Source

    Humanized (from mouse)

    Target

    VEGF-A

    Clone

    Monoclone

    Molecular Weight

    48 kDa

    Formula

    C2158H3282N562O681S12

    Antibody Form

    Purified immunoglobulin

    Physical Form

    Solution

    Grade Standard

    Medicine Grade

    Place of Origin

    China(Mainland)

    Storage

    -70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light.


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